Using textiles and pipettes for new organs

Warp knitted spacer fabrics as the base structure for 3-dimensional cell culture Learn more

3D textiles offer numerous advantages over their 2-dimensional counterparts, paving the way for applications in a wide range of industries, such as the automotive and construction sectors. Applications in medical technology are also being researched and expanded with growing interest, especially at the Institute for Textile Technology (ITA) at RWTH Aachen University. The Medical Textiles division of the renowned research institution primarily works with warp knitted 3D textiles, so-called spacer fabrics. Tissue engineering is one particular focus of the spacer fabric projects; it combines medicine and technology to produce artificial tissue implants or organ-like structures called organ modules. 1

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Footnotes
  • S. Patra, V. Young: A review of 3D printing techniques and the future in biofabrication of bioprinted tissue, in: Cell Biochemistry and Biophysics 74 (2), DOI: 10.1007/s12013-016-0730-0, 2016, pp. 93 – 98.
  • A. Roye, J. Stüve, T. Gries: Definition for the differentiation of 2-D and 3-D textiles, in: Technical Textiles, 2005.
  • E. Maeda, Y. Hagiwara, J. H. C. Wang, T. Ohashi: A new experimental system for simultaneous application of cyclic tensile strain and fluid shear stress to tenocytes in vitro, in: Biomedical Microdevices 15 (6), DOI: 10.1007/s10544-013-9798-0, 2013, pp. 1.067 – 1.075.
  • J. Zhu, J. Li, B. Wang, W. J. Zhang, G. Zhou, Y. Cao, W. Liu: The regulation of phenotype of cultured tenocytes by microgrooved surface structure, in: Biomaterials 31 (27), DOI: 10.1016/j.biomaterials.2010.05.058, 2010, pp. 6.952 – 6.958.
  • S. Patra, V. Young: A review of 3D printing techniques and the future in biofabrication of bioprinted tissue, in: Cell Biochemistry and Biophysics 74 (2), DOI: 10.1007/s12013-016-0730-0, 2016, pp. 93 – 98.
  • H. Ren, X. Shi, L. Tao, J. Xiao, B. Han, Y. Zhang et al.: Evaluation of two decellularization methods in the development of a whole-organ decellularized rat liver scaffold, in: Liver International 33 (3), DOI: 10.1111/liv.12088, 2013, pp. 448 – 458.
  • T. Bolle: Verstärkungsstrukturen für den Einsatz im myokardialen Tissue Engineering, Dissertation, RWTH Aachen, 2019.
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